Malignant Rhabdoid Tumor of Kidney

In a review of 111 cases of MRT of kidney by the National Wilms’ Tumor Study (Weeks, 1989) the median age at diagnosis was 11 months (range 0 – 106 months) and the male: female ratio was 1.5:1. Treatment for MRT of kidney is often similar to that for Wilms’ tumor (MRT starting in the brain or other non-renal sites have different treatments). A common cytogenetic feature of MRT is deletion of material from chromosome 22q11.2 including the SMARCB1 (SNF5/INI1) gene.

More About Malignant Rhabdoid Tumor of Kidney

Malignant Rhabdoid Tumor (MRT) of kidney is an aggressive sarcomatous neoplasm with a histology distinct from Wilms' tumor.


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