Langerhan’s Cell Histiocytosis

LCH is more common in children but it is often seen in adults too. The disease will be classed as either single-system or multi-system depending on how many of the body’s systems are effected. In a study of 314 people treated for LCH at the Mayo Clinic (Howarth et al, Cancer 1999;85:2278-90) 69% had single-system disease and 31% had multi-system LCH. Approximately half of those treated at Mayo were under 25 years old at diagnosis. Of people with single-system disease the system involved was bone (52%), pulmonary (lung) (40%), skin/mucous membrane (7%) and other sites (1%). Bone involvement was more common in younger patients while pulmonary involvement was mostly seen in those over 15 years old at diagnosis.

More About Langerhan’s Cell Histiocytosis

Langerhan's Cell Histiocytosis (also known as Histiocytosis X) is a rare disease. It is not really a cancer, though Histiocytes are normal cells found throughout the body, in this disease abnormally large numbers are found.


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